Method Development for the High-Performance Liquid Chromatographic Enantioseparation of 2-Cyanocycloalkanols
نویسندگان
چکیده
منابع مشابه
Review High-performance liquid chromatographic enantioseparation of drugs containing multiple chiral centers on chiral stationary phases
In recent years there has been considerable interest in the synthesis and separation of enantiomers of organic compounds especially because of their importance in the biochemistry and pharmaceutical industry. High-performance liquid Chromatography is a very useful method for the direct separation of enantiomers. However, about 30−40 years ago, commercially available chiral stationary phases wer...
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Easily degradating and various isomeric forms of rapamycin (Sirolimus) face the determination of this compound to many challenges. In this study, we developed and validated the isocratic reversed phase high performance liquid chromatographic (RP-HPLC) method for rapamycin. Separation was performed on a C8 column (MZ, 15 × 4.6 mm, 5 µm particle size) using methanol:water (80:20 v/v) as the mobil...
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ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2001
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/39.5.188